Weighted analysis of composite endpoints with simultaneous inference for flexible weight constraints
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چکیده
منابع مشابه
Weighted analysis of composite endpoints with simultaneous inference for flexible weight constraints
Composite endpoints are widely used as primary endpoints of randomized controlled trials across clinical disciplines. A common critique of the conventional analysis of composite endpoints is that all disease events are weighted equally, whereas their clinical relevance may differ substantially. We address this by introducing a framework for the weighted analysis of composite endpoints and inter...
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ژورنال
عنوان ژورنال: Statistics in Medicine
سال: 2016
ISSN: 0277-6715
DOI: 10.1002/sim.7147